3-Amino-2-methylbenzyl alcohol

3-Amino-2-methylbenzyl alcohol - Names and Identifiers

Name	3-Amino-2-Methylbenzyl Alcohol
Synonyms	Oct-7-enylamine (3-Amino-2-methylphenyl) 3-Amino-2-methylbenzyl alcohol 3-Amino-2-Methylbenzyl Alcohol 3-AMINO-2-METHYLBENZYL ALCOHOL (3-amino-2-methylphenyl)methanol Benzenemethanol, 3-amino-2-methyl-
CAS	83647-42-1

3-Amino-2-methylbenzyl alcohol - Physico-chemical Properties

Molecular Formula	C8H11NO
Molar Mass	137.18
Density	1.126±0.06 g/cm3(Predicted)
Melting Point	106-108 °C (lit.)
Boling Point	300.8±27.0 °C(Predicted)
Appearance	Powder
Color	Off-white to light orange/purple
pKa	14.53±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature

3-Amino-2-methylbenzyl alcohol - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3

3-Amino-2-methylbenzyl alcohol - Reference Information

use

3-amino -2-methylbenzyl alcohol can be used as an intermediate in pharmaceutical synthesis.

preparation

iron powder (183mg,3.29mmol) and ammonium chloride (22mg,0.419mmol) were added to the solution of stirred (2-methyl -3-nitro-phenyl)-methanol (13)(100mg,0.598mmol) in EtOH(5mL) and water (1mL), and the obtained mixture was refluxed for 2 hours. The reaction mixture was then raised to room temperature and filtered through a bed of diatomaceous earth. The filtrate was diluted with EtOAc, washed with water, dried and concentrated with sodium sulfate under reduced pressure to obtain 3-amino-2-methylbenzyl alcohol (70mg,85%), which was a yellow jelly.

Last Update：2024-04-09 21:11:58